By Irfan Mahmud, Pharmacist & Independent Prescriber

What to avoid when taking weight loss medication to ensure the best results

Weight loss medication can support your progress, but it works best when paired with habits that help your body respond well. Knowing what to avoid can make a significant difference in how effective the treatment is and how well you feel while taking it. Here are the key things to steer clear of.

1. Skipping meals

Because many weight loss medications reduce appetite, it can be tempting to skip meals entirely. Doing so may:

Reduce your energy levels

Affect your nutrient intake

Slow your metabolism over time

Aim for balanced, regular meals, even if they are smaller. Your body still needs steady nourishment.

2. Eating too little

Very low calorie intake can work against your goals. It may lead to fatigue, cravings, nutrient deficiencies and plateaus. A sustainable approach is more effective than extreme restriction.

3. Relying solely on the medication

Medication is a tool, not a replacement for healthy habits. Without supportive routines, results may be limited. Continuing to focus on nutrition, movement, hydration and sleep helps the medication work at its best.

4. Ignoring side effects

If you experience side effects such as nausea, changes in digestion or headaches, do not ignore them or try to push through. Keeping track and discussing them with your healthcare provider is important. Adjustments may be needed, and addressing issues early often leads to better long term results.

5. Drinking alcohol excessively

Alcohol can interfere with weight loss efforts by adding unnecessary calories and affecting appetite and decision making around food. It may also interact with some medications. If you drink, do so in moderation and be mindful of how it affects you.

6. Relying on high sugar or highly processed foods

These foods can cause blood sugar spikes, cravings and energy crashes. While there is no need to cut anything out completely, reducing highly processed snacks, sugary drinks and fast food can support steadier progress and help you feel better day to day.

7. Over exercising or pushing too hard

More exercise is not always better. Overdoing it can lead to injury, burnout and increased hunger. Consistency is more valuable than intensity. Gentle to moderate activity tends to be more manageable and sustainable.

8. Taking other supplements or medications without checking

Some supplements or over the counter products can interact with weight loss medication. Always check with a healthcare professional before adding anything new.

9. Expecting rapid or extreme results

Medication can support gradual, steady weight loss, but it is not a quick fix. Setting realistic expectations can help you stay motivated and reduce frustration.

10. Stopping the medication without guidance

If you feel unsure, are experiencing side effects, or feel the medication is not working as expected, speak with your healthcare provider before stopping. Proper guidance helps prevent unwanted weight regain or complications.

Reviewed by Irfan Mahmud, Pharmacist & Independent Prescriber (GPhC Reg. No: 2080386)

Irfan is a UK-registered pharmacist and independent prescriber with expertise in weight management, primary care, and lifestyle medicine. As the founder of Cuva Health, he is dedicated to providing safe, clinically-approved treatments and clear, trustworthy health guidance.