By Irfan Mahmud, Pharmacist & Independent Prescriber

Maintenance dose on Mounjaro

Reaching your target weight is a major milestone, but maintaining it can be just as important. For some patients, continuing Mounjaro at a lower dose can help stabilise appetite, support long term habits and reduce the risk of regaining weight. Here is what to know about using a maintenance dose safely and effectively.

Why a maintenance dose may be useful

Once you have reached your goal weight, your body naturally tries to return to its previous set point. This can make appetite increase, energy dip and weight maintenance feel more challenging. A maintenance dose of Mounjaro can help by:

Supporting appetite control

Preventing large fluctuations in hunger

Helping maintain routine eating patterns

Reducing the likelihood of early weight regain

The aim is stability, not further weight loss.

Choosing the right dose

A maintenance dose is usually lower than the dose used during active weight loss. The exact dose depends on:

Your previous response to Mounjaro

How sensitive you are to side effects

How stable your weight has been

Your eating patterns and hunger cues

The goal is to find a dose that supports maintenance without pushing your weight lower.

How long you can continue Mounjaro for maintenance

Many patients can continue until their BMI reaches around 22, although this is not a fixed rule. Each case is reviewed individually, taking into account:

Your overall health

How stable your weight has been

Any ongoing side effects

Your goals and lifestyle

Some people may benefit from longer use, while others may gradually stop sooner. The decision is tailored to each patient.

Regular reviews matter

Ongoing check ins with a clinician ensure the dose remains suitable. During reviews, your clinician may assess:

Your weight trend

Appetite patterns

How you feel on your current dose

Any changes in health or medication

Whether adjustments are needed

These reviews help prevent unnecessary dose changes and support safe, steady maintenance.

Maintaining healthy routines alongside medication

A maintenance dose works best when paired with consistent, realistic habits. Helpful routines include:

Balanced meals with plenty of protein and fibre

Regular physical activity that you enjoy

Staying hydrated

Keeping a steady sleep routine

Monitoring your hunger cues and energy levels

These habits reduce your reliance on medication over time.

When to consider reducing or stopping

You may consider adjusting or discontinuing Mounjaro if:

Your weight has been stable for a while

You no longer feel appetite changes on your dose

You are confident in your long term lifestyle habits

Your clinician advises a gradual reduction

Stopping is always done step by step to avoid sudden changes in appetite.

Final thoughts

A maintenance dose of Mounjaro can be a helpful tool for keeping your weight steady after reaching your goal. The focus is on stability, comfort and long term health, not ongoing weight loss. With individual review and the right dose, many patients maintain their progress confidently and safely.

Reviewed by Irfan Mahmud, Pharmacist & Independent Prescriber (GPhC Reg. No: 2080386)

Irfan is a UK-registered pharmacist and independent prescriber with expertise in weight management, primary care, and lifestyle medicine. As the founder of Cuva Health, he is dedicated to providing safe, clinically-approved treatments and clear, trustworthy health guidance.